Background-Continuous positive airway pressure (CPAP) with fixed mask press
ure is the current standard treatment for obstructive sleep apnoea (OSA). A
uto-CPAP devices apply at any time the minimally required pressure to norma
lise breathing and may improve patient comfort and compliance. We present a
n open descriptive study of auto-CPAP treatment at home in patients previou
sly managed with conventional CPAP.
Methods-Fifteen patients with obstructive sleep apnoea (OSA), previously tr
eated for at least one year with standard CPAP, were followed prospectively
for a two month period on auto-CPAP. Outcome measures were both subjective
evaluation by the patients and objective (polysomnographic) data obtained
at one and two months of follow up.
Results-The Epworth sleepiness score did not change significantly between b
aseline and follow up after one and two months and no systematic changes in
CPAP related side effects were reported. Compared with the baseline polyso
mnographic values without treatment, a significant improvement in both resp
iratory and sleep parameters was observed during auto-CPAP. These results w
ere not significantly different from those obtained with standard CPAP. A s
ignificant correlation was found between the effective CPAP pressure (Peff)
and the amount of time spent below Pelf during auto-CPAP treatment (r = 0.
6, p = 0.01).
Conclusion-Long term auto-CPAP treatment in these patients with severe OSA
appears to provide comparable efficacy to that of standard CPAP treatment.