Rapid and efficient production of L-lactate from xylose using electrodialysis culture-associated product separation

L-Lactate was produced from xylose using electrodialysis culture (ED-C)-ass ociated product separation. In a medium containing 50 g xylose/l, the ED-C was completed in only 32 h (i.e. less than half the time taken by the contr ol culture, without electrodialysis). At 80 g xylose/l, the control culture was unable to consume more than 50 g xylose/l, whereas the ED-C showed inc reased xylose consumption and was completed by 45 h. The maximum rate of la ctate production in the ED-C was higher than that in the control culture. E D-C was also carried out (at 80 g initial xylose/l) with a supply of fresh xylose-free medium. This ED-C was completed within 30 h, which represents a reduction in fermentation time of 15 h when compared to ED-C without addit ion of xylose-free medium. Thus, rapid production of L-lactate was achieved by using ED-C which supplied fresh xylose-free medium.