New methods for minimal invasive work-up of mammographic or MR-detected lesions

Results of 3 minimal invasive techniques for breast biopsy of clinically oc cult lesion are presented. 1. Mammographically guided Site-Select biopsies allow removal tissue in one piece using a large diameter core biopsy instrument (simular to the ABBI-p rinciple). However the overlying subcutaneous tissue is saved. No technical problems occurred in 13/13 diagnostic biopsies. Complete removal was, howe ver, only possible in 2/4 tumors < 1 cm due to tissue shift during insertio n of the instrument. 2. Mammographically guided vacuum biopsy also allows contiguous removal of areas of 1.2-1.8 cm diameter, while blood is suctioned out, as well. 3 ster eotaxic miscalculations were immediately recognized. Diagnostic accuracy in 405 biopsies so far is 100 %. The examination was very well tolerated by t he patients. 3. By means of a specially developed biopsy coil and vacuum biopsy percutan eous in- or excisional biopsy of enhancing lesions visible by MRI alone has been realized by us for the first time. 24/25 diagnoses are definitely rep resentative - as proven by lack of enhancement after biopsy. One diagnosis, which was uncertain due to overlying blood, is being followed. Minimal inv asive methods may open up new perspectives.