THE CHEMISTRY OF INDOLES .80. SYNTHETIC STUDY DIRECTED TOWARD NOVEL MULTILINKED HETEROCYCLES

Authors
SOMEI M YAMADA Y KITAGAWA K SUGAYA K TOMITA Y YAMADA F NAKAGAWA K
Citation
M. Somei et al., THE CHEMISTRY OF INDOLES .80. SYNTHETIC STUDY DIRECTED TOWARD NOVEL MULTILINKED HETEROCYCLES, Heterocycles, 45(3), 1997, pp. 435-438
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
3
Year of publication
1997
Pages
435 - 438
Database
ISI
SICI code
0385-5414(1997)45:3<435:TCOI.S>2.0.ZU;2-I
Abstract
2-Amino-4-(1-methylindol-3-yl)thiazole (11c) has a characteristic nucl eophilic nature at the 5-position and add to the 4-position of acetylp yridinium acetate (13) producing cetylamino-5-(1-acetyl-1,4-dihydropyr idin-4-yl)-4- (1-methylindol-3-yl)thiazole (1c). Its structure was est ablished by X-ray single crystallographic analysis. Applying the resul ts, simple syntheses of the related tris- (1a-b and 2-8) and tetrakis- linked heterocycles (9) were achieved.