3-AMINO-2(1H)-QUINOLONES BY CYCLIZATION OF N-ACYLATED ANTHRANILIC ACID-DERIVATIVES

Authors
REHWALD M GEWALD K LANKAU HJ UNVERFERTH K
Citation
M. Rehwald et al., 3-AMINO-2(1H)-QUINOLONES BY CYCLIZATION OF N-ACYLATED ANTHRANILIC ACID-DERIVATIVES, Heterocycles, 45(3), 1997, pp. 483-492
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
45
Issue
3
Year of publication
1997
Pages
483 - 492
Database
ISI
SICI code
0385-5414(1997)45:3<483:3BCONA>2.0.ZU;2-L
Abstract
Reaction of secondary amines with the N-(iodoacetyl)anthranilic acid d erivatives, 2-(iodoacetylamino)acetophenone and 2-(iodoacetylamino)ben zophenone yields 3-amino-2(1H)-quinolones in two steps. Analogously he terocondensed 5-amino-6(7H)-pyrazolo[5,4-b]pyridones were prepared. Hy droxyquinolines were subjected to Cl/OH exchange to give chloroquinoli nes, which are convenient for consecutive reactions.