Third degree atrioventricular block with alpha interferon: a case report.

Iatrogenic third degree atrioventricular block due to alpha interferon is r are. The authors present a case which occured with low dosage, regressed when tr eatment was withdrawn and reappeared when treatment was reintroduced. The p hysiopathological mechanism of disease of the conduction pathways and its g eneral cardiotoxicity is not yet understood. The secondary effects of this increasingly widely used anti-tumoral and ant i-infectious drug should be recognised in order to prevent them. Initial ca rdiological investigation and follow-up are indicated to ensure this preven tion.