Antimutagenic effect of copper (II) complexes

Mutagenic and antimutagenic activity of copper (II) niflumate, copper (II) salicylate and their ronicol adducts were studied on the bacterial system S almonella typhimurium. Cu (II) complexes did not significantly increase the number of spontaneous revertants and showed no mutagenic activity. The mos t significantly decreased mutagenic effect was observed in the promutagens 2-aminoanthracene and 2-aminofluorene following the treatment with all Cu ( II) complexes, as compared to the control.