Production of dihoma-gamma-linolenic acid by Mortierella alpina

Mortierella alpina CCF 185 was used for the production of dihomo-gamma-lino lenic acid (DGLA) in submerged and solid state regime. Under submerged cond itions, the fungus was cultivated in glucose medium supplemented with sesam e oil and non-oil acetone extract. Solid state cultivation was carried out on crushed sesame seeds. The maximal yield of DGLA was 475 mg/L in submerge d fermentation, and 21.3 g/kg of residual substrate in solid state cultivat ion.