Potential carcinogenicity of some transition metal ions

Authors
Dovinova, I Vachalkova, A Novotny, L
Citation
I. Dovinova et al., Potential carcinogenicity of some transition metal ions, BIOL TR EL, 67(1), 1999, pp. 63-73
Citations number
35
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
BIOLOGICAL TRACE ELEMENT RESEARCH
ISSN journal
01634984 → ACNP
Volume
67
Issue
1
Year of publication
1999
Pages
63 - 73
Database
ISI
SICI code
0163-4984(199901)67:1<63:PCOSTM>2.0.ZU;2-X
Abstract
Potential carcinogenicity of some transition metal ions was tested using a direct-current polarography method. The measurements were based on the redu ction of tested compounds in an anhydrous solution using alpha-lipoic acid as the detection compound. The potential carcinogenicity was expressed in t erms of the parameter tg alpha, which is known to directly correlate with t he carcinogenicity of tested compounds. For the metal ions tested, tg alpha was found to decrease in the following sequence: Fe(III) > Pb(II) > V(IV) > Fe(II) > Mn(II) > Cu(II). Zero values of tg alpha were found for Cd(II) a nd Mn(III).