Decreases in molecularity promote conversion when reactions are catalyzed by enzymes immobilized in slab-shaped beads

Application of Fick's first law to substrate undergoing chemical reaction c atalyzed by an enzyme immobilized in a porous slab-shaped bead leads to sub strate concentration profiles that are flatter when the ratio of stoichiome tric coefficients of product to reactant (v) is lower. Since the actual eff ectiveness factor decreases when v increases (at approximately the same rat e irrespective of the value taken by the Michaelis-Menten parameter). then considerable overprediction of the conversion levels obtained within a give n reaction timeframe will occur if the simplistic land more easily modelled ) situation of equimolar counterdiffusion is taken for modelling purposes w hen v>1.