Correlation of periurethral bacterial flora with bacteriuria and urinary tract infection in children with neurogenic bladder receiving intermittent catheterization

Citation
Ta. Schlager et al., Correlation of periurethral bacterial flora with bacteriuria and urinary tract infection in children with neurogenic bladder receiving intermittent catheterization, CLIN INF D, 28(2), 1999, pp. 346-350
Citations number
18
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
28
Issue
2
Year of publication
1999
Pages
346 - 350
Database
ISI
SICI code
1058-4838(199902)28:2<346:COPBFW>2.0.ZU;2-8
Abstract
Periurethral bacteria are inoculated daily into the urine of children with neurogenic bladder during clean intermittent catheterization (CIC). We exam ined how frequently periurethral bacterial species produced bacteriuria in children followed longitudinally. When Escherichia coli was detected on the periurethra, bacteriuria was also present 93% of the time. When Klebsiella , Pseudomonas, or Enterococcus species or nonpathogens were detected on the periurethra, bacteriuria was present 80%, 40%, 40%, and 25% of the time, r espectively. Clonal typing of multiple colonies of E. coli from each periur ethral and urine culture revealed that children carried only one or two E, coli clones in their urinary tracts over months of surveillance. When E, co li was detected in the urine, the identical clone was on the periurethra. E . coli persisted for weeks in the urine without causing symptoms. Occasiona lly the same E. coli clone carried for weeks caused a urinary tract infecti on. Bacteriuria frequently occurs after inoculation of periurethral E. coli into the urine during CIC.