Molecular genetic approaches to understanding the actin cytoskeleton

Authors
Sutherland, JD Witke, W
Citation
Jd. Sutherland et W. Witke, Molecular genetic approaches to understanding the actin cytoskeleton, CURR OP CEL, 11(1), 1999, pp. 142-151
Citations number
103
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN CELL BIOLOGY
ISSN journal
09550674 → ACNP
Volume
11
Issue
1
Year of publication
1999
Pages
142 - 151
Database
ISI
SICI code
0955-0674(199902)11:1<142:MGATUT>2.0.ZU;2-K
Abstract
New tools in molecular genetics, such as genetic interaction screens and co nditional gene targeting, have advanced the study of actin dynamics in a nu mber of model systems. Yeast, Dictyostelium, Caenorhabditis elegans, Drosop hila, and mice have contributed much in recent years to a better understand ing of both the numerous functions and modes of regulation of the actin cyt oskeleton.