A 55-year-old black man with two firm intradermal nodules of the scrotum is
presented. On histopathologic examination, the nodules were determined to
be cutaneous granular cell tumors. This was confirmed by strong immunohisto
chemical reactivity to S-100 protein, There are no previous reports of mult
iple granular cell tumors of the male genitalia. Only one report of a solit
ary granular cell tumor of the scrotum appears in the literature.