Fine needle aspiration (FNA) biopsy of primary cutaneous meningioma: report of two cases

Two cases of primary cutaneous meningioma are described. A male and a femal e patient, aged 56 and 61 years, respectively, presented each with a solita ry subepidermal nodule, The initial diagnosis was established in both patie nts by application of FNA biopsy. The subsequent histologic examination con firmed the cytologic diagnosis, Extensive investigation of the patients by computed tomography (CT) and nuclear magnetic resonance imaging (MRI) scans failed to reveal any primary meningioma of the neuraxis, Neurologic examin ation and routine laboratory test results were all normal. The microscopic features, immunocytological study and histology, which all gave a similar p attern to that seen in intracranial meningiomas, are discussed. Distinction from other cutaneous lesions that may be considered in the differential di agnosis is made, A brief review of the literature is also presented.