B. Wigginghaus et al., Primary palliative treatment of malignant gastric outlet obstruction with a selfexpanding metal stent, DEUT MED WO, 124(5), 1999, pp. 109-113
Citations number
30
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Background and objective: A high operative mortality, diffuse local tumor g
rowth and abnormal wound healing are significant risk factors in the pallia
tive surgical treatment of gastric outlet obstruction caused by a malignant
tumor. This study was undertaken to evaluate the use of selfexpanding meta
l stents as an alternative.
Patients and methods: Over a period of 33 months, nine previously unoperate
d patients (three women, six men; mean age 71,4 [66-76] years) with gastric
outlet obstruction by a malignant tumor underwent endoscopic implantation
of an uncoated self-expanding nitinol Ultraflex stent. The stent's length w
as 7 and 10 cm, respectively, the length of the carrier catheter was 92 cm.
The stent was implantated after balloon dilatation of the stenosis and mar
king the distal tumor margin with lipiodol injected over a guide-wire under
fluoroscopic control.
Results: The implantation was successful in only two of the first five pati
ents, but after modifying the method of stent release in three of the four
subsequent patients. All patients reported an improved quality of life. One
patient died after 10 days of the underlying malignancy. There were no com
plications associated with the implantation.
Conclusions: Insertion of a self-expanding metal stent can provide pallatio
n in patients with inoperable gastric outlet stenosis due to malignant tumo
ur. The number of successful implantations can probably be increased by opt
imizing some of the devices used, for example by lengthening the carrier ca
theter.