Small-cell carcinoma of the rectum is an infrequent pathologic finding, and
its precise incidence is unknown. Its incidence is less than 0.2 percent a
mong all colorectal cancers. This tumor manifests highly; aggressive behavi
or. The treatment of choice is combination chemotherapy similar to that use
d for small-cell carcinoma of the lung, but in small localized tumors surge
ry plus chemotherapy is an alternative. We present two cases of small-cell
carcinoma of the lower rectum and a review of the literature.