K. Pierzchala-koziec et al., Acute reserpine treatment alters the catecholamine, glucocorticoid and opioid response to walking exercise in sheep, EXP CL E D, 107(1), 1999, pp. 85-88
Citations number
13
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
The aim of the study was to examine the effects of reserpine on the plasma
levels of adrenaline, noradrenaline, cortisol and alpha-neoendorphin in she
ep under control conditions and during walking exercise. One hour of walkin
g (5 km/h) caused a significant increase in both catecholamines and cortiso
l between 10 and 30 min of stress, and transiently decreased the level of a
lpha-neoendorphin at the same time. Reserpine at the dose of 0.3 mg/kg i.v.
given before stress significantly lowered the basal levels of all tested p
arameters. A combination of the reserpine and walking exercise significantl
y attenuated the stress-induced changes in the plasma level of measured hor
mones.