One of the most important and difficult decision-making tasks is that of in
terpreting three-dimensional (3D) medical imagery. This information-intensi
ve task typically requires expediency, accuracy and reliability in both the
Visual presentation as well as in the interpretation of complex informatio
n. We present an approach that facilitates this task by using domain knowle
dge to assist in the interpretation and visualization of 3D cardiac imagery
. The objective is to provide the clinician with a more efficient, reliable
, comprehensive, and clinically useful manner with which to accurately inte
rpret and display large amounts of complex information. These objectives ar
e met by capturing and representing the Visual reasoning process in a compu
tational model, and providing the user with an intuitive graphical and text
ual representation of the data, as well as explanations, justifications, an
d interactive data visualizations. The approach is illustrated with cardiov
ascular 3D SPECT tomographic perfusion imagery, a technique aimed at diagno
sing heart disease. (C) 1999 Elsevier Science B.V. All rights reserved.