Bh. Kim et al., 2-BROMO-2-NITROPROPANE ZN PROMOTED REDUCTIVE CYCLIZATIONS OF ORTHO-SUBSTITUTED NITROARENES TOWARD 2,1-BENZISOXAZOLE DERIVATIVES/, Heterocycles, 45(2), 1997, pp. 235-240
Under the mild conditions, reductive cyclizations of 2-nitrobenzaldehy
des or 2'-nitroacetophenone towards 2,1-benzisoxazoles were accomplish
ed in the presence of 2 bromo-2-nitropropane/Zn in methanolic solution
. The synthetic utility and the role of 2-bromo-2-nitropropane were in
vestigated.