Octreotide induced remission of a refractory small cell carcinoma of the endometrium

This is the first report of remission obtained with octreotide in a woman d iagnosed with recurrent small cell carcinoma of the endometrium with neuroe ndocrine features, refractory to a combination of etoposide, cisplatin, and radiation therapy. Stabilization of disease was obtained with a combinatio n of tamoxifen and leuprolide depot. Regression of disease was then achieve d by the addition of octreotide. The use of octreotide as an antitumor agen t is reviewed.