Evaluation of the fungitest kit by using strains from human immunodeficiency virus-infected patients: Study of azole drug susceptibility

Citation
F. Witthuhn et al., Evaluation of the fungitest kit by using strains from human immunodeficiency virus-infected patients: Study of azole drug susceptibility, J CLIN MICR, 37(3), 1999, pp. 864-866
Citations number
17
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
37
Issue
3
Year of publication
1999
Pages
864 - 866
Database
ISI
SICI code
0095-1137(199903)37:3<864:EOTFKB>2.0.ZU;2-J
Abstract
One hundred eighteen Candida clinical isolates from human immunodeficiency virus-infected patients were tested for their susceptibilities to fluconazo le and itraconazole by Fungitest and the National Committee for Clinical La boratory Standards MIC method. Fungitest results depended on both yeast spe cies and antifungal agents. This test is able to detect sensitive strains ( 97% agreement with results of the MIC method in tests with fluconazole and 84% agreement in tests with itraconazole) but has a poor capacity to detect resistant strains (26% agreement in tests with fluconazole and 5% agreemen t in tests with itraconazole).