This 55-year-old man presented with malignant intravascular lymphomatosis,
a rare vascular disorder of the central nervous system characterized by pro
liferation of malignant lymphoma cells. The clinical manifestations were fo
cal neurological signs and progressive dementia. Angiography demonstrated s
tenoses of the cortical veins. Postmortem examination revealed infiltration
of tumor cells into the lumen and Vascular wall, although the stenoses wer
e caused primarily by fibrin thrombi. To the authors' knowledge this is the
first case of malignant intravascular lymphomatosis associated with venous
stenosis.