Neurological complications arising from schistosomiasis are uncommon, and r
eports of Manson's schistosomiasis presenting as an intracerebral mass lesi
on are particularly rare. The authors describe the case of a 26-year-old ma
n with a 3-month history of headaches and visual abnormalities. He had immi
grated to Canada from Brazil 4 years previously. The patient's general phys
ical and neurological examinations were unremarkable. Magnetic resonance (M
R) imaging revealed an enhancing lesion with surrounding edema and mild mos
s effect in the right occipital lobe. A stereotactic brain biopsy demonstra
ted intraparenchymal granulomas surrounding Schistosoma masoni eggs. The pa
tient's symptoms resolved following treatment with praziquantel and steroid
medications; follow-up MR imaging yielded normal findings. This case demon
strates that neuroschistosamiasis should be considered when an individual p
resenting with an intracerebral mass has lived in a region in which this di
sease is endemic.