A new germacrane sesquiterpene from the Brazilian endemic gorgonian Phyllogorgia dilatata Esper

A bioassay-guided re-investigation of natural products from the Brazilian e ndemic octocoral Phyllogorgia dilatata Esper (Gorgonacea, Gorgoniidae), col lected in Rio de Janeiro State, has revealed three further compounds from t his species: the dinoflagellate pigment peridinin (1), the icthyodeterrent diterpene 1 1 beta, 12 beta-epoxypukalide (2), both previously reported fro m other octocoral species, and the new natural sesquiterpene (E) germacra- 1(10),4(15),7(1 1)-trien-5-ol-8-one (3). Spectroscopic analysis and compari son with literature data allowed the structure elucidation of 1-3.