The purpose of this investigation was to evaluate the value, accuracy,
and operational feasibility of indicators/criteria in a drug use eval
uation (DUE) examining IV histamine(2)-receptor antagonists (H-2-RA).
Pharmacists in 40 hospitals collected DUE data concurrent with hospita
l stays on a total of 1,200 patients. After completing the DUE, pharma
cist data collectors were asked to evaluate each DUE criterion. Most r
eported that criteria relating to indications for use, therapeutic dru
g monitoring, and adverse drug reactions/drug interactions should be i
ncluded in a DUE, but some criteria were not easy to collect or were i
naccurate. The data suggest the need to carefully select DUE criteria
that can be used for continuous improvements that meet JCAHO accredita
tion requirements.