The survival chain: The delay to restoration of spontaneous circulation is
the key to prognosis of cardiac arrest occurring outside the hospital. Amon
g the many etiologies of cardiac arrest sudden onset ventricular fibrillati
on is the number one cause of sudden death in adults. Better prognosis depe
nds on effective organisation founded on the concept of a "survival drain".
Alert and resuscitation: By alerting the emergency units and performing the
basic gestures of cardiopulmonary resuscitation (freeing the airways, mout
h-to-mouth ventilation and closed chest cardiac massage) those witnessing t
he event take the first steps in the survival chain while waiting for the p
aramedical and medical teams to arrive.
Defibrillation: In case of ventricular fibrillation, prognosis is directly
related to the delay to defibrillation. Defibrillators used by specially tr
ained paramedics before a physician arrives on the scene have considerably
improved prognosis.
Specialized resuscitation: Precise algorithms help guide treatment in accor
dance with the observed cardiac rhythm. Tracheal intubation and artificial
ventilation are fundamental. Among the useful drugs, epinephrine is by far
the most important for improving myocardial and cerebral perfusion, improvi
ng the chances of recovering spontaneous circulation. The only anti-arrhyth
mic drug currently used is lidocaine infusion of alkaline fluid is only use
ful in specific cases of prolonged resuscitation. Expired CO2 monitoring ma
y be a useful guide, but discontinuing resuscitation is strictly a medical
decision.
After resuscitation: When spontaneous circulation has been achieved, the pa
tient must be transported to a cardiac hospital for specialized care and et
iological treatment.