Plummer-Vinson syndrome in children. A report of three cases.

Three cases of Plummer-Vinson syndrome in girls aged 11 to 15 years are rep orted. All three patients presented with proximal dysphagia and chronic ane mia. The exact role of iron deficiency in Plummer-Vinson syndrome remains u nclear. The diagnosis rests on demonstration of an esophageal web by opacif ication or endoscopic evaluation of the esophagus, The dysphagia and the es ophageal constriction resolve after iron store replenishment, Plummer-Vinso n syndrome is associated with a high risk of esophageal cancer.