Utilization of multivariate calibration methods for the study of K+ transport through hydrophobic liquid membranes by using isomeric anions

This work describes utilization of the multivariate calibration method PLS (partial least squares) in the investigation of K+ transport through a chol oroform membrane by using mixtures of three isomeric organic anions as coun terions. A comparison between the results obtained by this method and those obtained by the stepwise multiple linear regression method was also made. The BLM (bulk liquid membrane) method was employed in the transport by usin g a neutral crown ether, 18-crown-6 (18C6) as the carrier. Multivariate cal ibration was necessary since there are superpositions among the UV-Vis spec tra of the three isomers. Univariate methods are shown to be unable to quan tify samples in these conditions.