A new approach to the synthesis of 2-aminoimidazo[1,2-a]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines

Authors
Vega, JA Vaquero, JJ Alvarez-Builla, J Ezquerra, J Hamdouchi, C
Citation
Ja. Vega et al., A new approach to the synthesis of 2-aminoimidazo[1,2-a]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines, TETRAHEDRON, 55(8), 1999, pp. 2317-2326
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
8
Year of publication
1999
Pages
2317 - 2326
Database
ISI
SICI code
0040-4020(19990219)55:8<2317:ANATTS>2.0.ZU;2-1
Abstract
A microwave (focused waves) assisted N-alkylation of 2-halopyridines provid es;a convenient entry to 2-amino-imidazo[1,2-a]pyridine derivatives after r eaction of the alkylated substrates with cyanamide under basic conditions. (C) 1999 Elsevier Science Ltd. All rights reserved.