Solid supported aryl/heteroaryl C-N cross-coupling reactions.

Authors
Combs, AP Saubern, S Rafalski, M Lam, PYS
Citation
Ap. Combs et al., Solid supported aryl/heteroaryl C-N cross-coupling reactions., TETRAHEDR L, 40(9), 1999, pp. 1623-1626
Citations number
6
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
9
Year of publication
1999
Pages
1623 - 1626
Database
ISI
SICI code
0040-4039(19990226)40:9<1623:SSACCR>2.0.ZU;2-P
Abstract
We report herein the first examples of polymer supported aryl-heteroaryl C- N cross-coupling reactions and dramatically decreased reaction times upon m icrowave irradiation; The methodology provides easy access to N-arylated he terocycles from heterocycles bearing an N-H bond and readily available aryl boronic acids in the presence of copper(II) acetate and pyridine. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.