The synthesis of water soluble dendrimers, and their application as possible drug delivery systems.

Authors
Twyman, LJ Beezer, AE Esfand, R Hardy, MJ Mitchell, JC
Citation
Lj. Twyman et al., The synthesis of water soluble dendrimers, and their application as possible drug delivery systems., TETRAHEDR L, 40(9), 1999, pp. 1743-1746
Citations number
9
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
9
Year of publication
1999
Pages
1743 - 1746
Database
ISI
SICI code
0040-4039(19990226)40:9<1743:TSOWSD>2.0.ZU;2-6
Abstract
The synthesis of two water soluble dendrimers is described. The formation o f water soluble inclusion complexes with a variety of small, hydrophobic gu est molecules is also described. Moreover, when these guest molecules are d rug moieties, then the resulting drug/dendrimer complexes can be considered ideal candidates for use as novel drug delivery systems. (C) 1999 Elsevier Science Ltd. All rights reserved.