Lafora bodies associated with neurologic signs in a cat

Lafora bodies (polyglucosan deposits) were identified in the brain of a you ng adult cat with neurologic signs characterized by intermittent but progre ssively worsening head and body tremors. The cerebellar cortex was the most severely affected area of brain, and the deposits were identified within P urkinje cell bodies and processes and throughout the neuropil. The associat ion of Lafora bodies with neurologic signs, occurrence of deposits within n euronal perikarya, and distribution primarily within the cerebellar cortex are features distinct from the more commonly recognized situation in which Lafora bodies occur as incidental lesions in cats.