Gliclazide

Citation
M. Parvez et al., Gliclazide, ACT CRYST C, 55, 1999, pp. 74-75
Citations number
13
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
55
Year of publication
1999
Part
1
Pages
74 - 75
Database
ISI
SICI code
0108-2701(19990115)55:<74:G>2.0.ZU;2-W
Abstract
The crystal structure of gliclazide, N-[(perhydrocyclopenta[c]pyrrol- 2-yl) aminocarbonyl]-p-toluenesulfonamide, C15H21N3O3S, a second-generation oral hypoglycemic agent, contains discrete molecules with normal molecular dime nsions. Both of the five-membered fused rings adopt envelope conformations. The molecules are linked into chains by intermolecular hydrogen bonds invo lving amino-H atoms, with N...O separations of 2.967(3) and 2.949 (3) Angst rom.