The crystal structure of gliclazide, N-[(perhydrocyclopenta[c]pyrrol- 2-yl)
aminocarbonyl]-p-toluenesulfonamide, C15H21N3O3S, a second-generation oral
hypoglycemic agent, contains discrete molecules with normal molecular dime
nsions. Both of the five-membered fused rings adopt envelope conformations.
The molecules are linked into chains by intermolecular hydrogen bonds invo
lving amino-H atoms, with N...O separations of 2.967(3) and 2.949 (3) Angst
rom.