This paper examines the validity of self-report of drug use in several impo
rtant high-risk samples by comparing survey answers with urinalysis results
. The analyses include data obtained from face-to-face interviews with 1536
patients in sexually transmitted disease (STD) clinics, 1564 patients in h
ospital emergency rooms (ERs), and 2034 recent arrestees in jails. Using ur
inalysis as the criterion measure, considerable underreporting was observed
, particularly among STD and ER subjects using cocaine and opiates. A logis
tic regression analysis on factors related to the underreporting was conduc
ted for both cocaine and opiates. The results showed that a lower degree of
underreporting was associated with subjects at jail sites (compared to STD
subjects) and those who self-reported lifetime drug dependence.