The central Siberian origin for Native American Y chromosomes

Citation
Fr. Santos et al., The central Siberian origin for Native American Y chromosomes, AM J HU GEN, 64(2), 1999, pp. 619-628
Citations number
45
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Molecular Biology & Genetics
Journal title
AMERICAN JOURNAL OF HUMAN GENETICS
ISSN journal
00029297 → ACNP
Volume
64
Issue
2
Year of publication
1999
Pages
619 - 628
Database
ISI
SICI code
0002-9297(199902)64:2<619:TCSOFN>2.0.ZU;2-5
Abstract
Y chromosomal DNA polymorphisms were used to investigate Pleistocene male m igrations to the American continent. In a worldwide sample of 306 men, we o btained 32 haplotypes constructed with the variation found in 30 distinct p olymorphic sites. The major Y haplotype present in most Native Americans wa s traced back to recent ancestors common with Siberians, namely, the Kets a nd Altaians from the Yenissey River Basin and Altai Mountains, respectively . Going further back, the next common ancestor gave rise also to Caucasoid Y chromosomes, probably from the central Eurasian region. This study, there fore, suggests a predominantly central Siberian origin for Native American paternal lineages for those who could have migrated to the Americas during the Upper Pleistocene.