An open, multivendor specification for high-throughput organic chemistry (HTOC): A flexible production process for pure, characterized, quantified organic compounds

Authors
Coffey, P Ramieri, J Garr, C Schultz, L
Citation
P. Coffey et al., An open, multivendor specification for high-throughput organic chemistry (HTOC): A flexible production process for pure, characterized, quantified organic compounds, AM LABORAT, 31(4), 1999, pp. 57
Citations number
1
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
AMERICAN LABORATORY
ISSN journal
00447749 → ACNP
Volume
31
Issue
4
Year of publication
1999
Database
ISI
SICI code
0044-7749(199902)31:4<57:AOMSFH>2.0.ZU;2-E
Abstract
Driven by competitive pressure to speed up the drug discovery process, phar maceutical companies have been compelled to change their approaches to lead development. This article discusses an automated, high-throughput manufact uring process to purify, characterize, and quantify large numbers of organi c compounds that are candidates for screening.