Segregation analysis of quantitative traits

Authors
Ginsburg, E Livshits, G
Citation
E. Ginsburg et G. Livshits, Segregation analysis of quantitative traits, ANN HUM BIO, 26(2), 1999, pp. 103-129
Citations number
103
Categorie Soggetti
Medical Research General Topics
Journal title
ANNALS OF HUMAN BIOLOGY
ISSN journal
03014460 → ACNP
Volume
26
Issue
2
Year of publication
1999
Pages
103 - 129
Database
ISI
SICI code
0301-4460(199903/04)26:2<103:SAOQT>2.0.ZU;2-T
Abstract
A review of advanced methods of segregation analysis of quantitative traits on human pedigree data is presented. Special attention was paid to formula tion of genetic models tested in the analysis, to the possibility of statis tical distinguishing between these models, to the power of the used transmi ssion probability tests, and to the possibility of unambiguous interpretati on of the analysis results.