Twenty-eight patients with average followup of 27 months (range, 12-51 mont
hs) required occipitocervical fusion with plates. A 1992 to 1996 consecutiv
e case series enrolled patients prospectively from two institutions. Five s
urgeons participated. Sixteen patients had inflammatory arthritis; four, os
teogenesis imperfecta; three, tumors; three, congenital anomalies; one, pse
udarthrosis after odontoid fracture; and one, osteoarthritis. Twenty-two of
28 (78.6%) patients had serious comorbid medical conditions. Additional ha
lo immobilization of 6 weeks was used in 16 of 27 patients. Four patients r
equired revision surgery. No patients showed a decline in neurologic status
and average neurologic improvement was one Nurick grade. Two-year followup
showed 13 (50%) excellent, nine (34.6%) good, two (7.7%) fair, and two (7.
7%) poor outcomes based on a functional outcome scale. There were three dea
ths during the follow up period (overall mortality rate of 10.7%). One deat
h was attributable to airway obstruction, one death 14 months postoperative
ly was attributable to late Methicillin resistant Staphylococcus aureus sep
sis at the bone graft donor site, and one death 41 months postoperatively w
as attributable to a stroke. The overall fusion rate was 85.2% (23 of 27 pa
tients), with a 96.3% (26 of 27 patients) occipitocervical fusion rate. Thr
ee patients had a possible asymptomatic end segment pseudarthrosis with scr
ew loosening. Twenty-two of 26 (84.6%) interviewed patients would choose th
e surgery again if given the choice.