We calculate the number of bound states appearing below the spectrum of a s
emi-bounded operator in the case of a weak, indefinite perturbation. The ab
stract result generalizes the Birman-Schwinger principle to this case. We d
iscuss a number of examples, in particular higher order differential operat
ors, critical Schrodinger operators, systems of second order differential o
perators, Schrodinger type operators with magnetic fields and the two-dimen
sional Pauli operator with a localized magnetic field.