Objective: This review of holmium laser resection of the prostate (HoLRP) s
ummarises the evolution, points of technique, results of clinical trials an
d ongoing research concerning this procedure. Methods: Over 3 years of expe
rience with holmium resection/enucleation in two institutions is reviewed.
Several open studies and 2 randomised trials are presented and the results
discussed. Current work with holmium enucleation of the prostate (HoLEP) in
combination with intracavitary morcellation is also reported. Results: HoL
RP results in fewer blood transfusions, less nursing contact time, less req
uirement for bladder irrigation, and a shorter catheter time and hospital s
tay than for patients treated with standard electrocautery resection of the
prostate (TURP). Preliminary results suggest equivalent symptomatic relief
, and relief of bladder outflow obstruction between the two procedures. Con
clusions: Holmium prostatectomy continues to evolve. Preliminary experience
suggests that it may be a viable alternative to TURF and appears to have s
ome significant advantages. Newer techniques for tissue retrieval may signi
ficantly decrease the operating time.