Multifocal fibrosclerosis presenting as Grave's orbitopathy - Bilateral exophthalmos associated with retroperitoneal and sellar fibrosis

Background: Multifocal fibrosclerosis (MF) is a rare disease that may be mi sdiagnosed as Graves orbitopathy. The combination of localisations of MF pr esented here has not been reported before. Case report: A 44-year-old man was referred with progressive bilateral exop hthalmos. CT of his chest and abdomen revealed an intrathoracic and retrope ritoneal peri-aortal soft-tissue process with hydronephrosis. Histological examination of orbital masses showed a fibrous process with low inflammator y activity. Later the sella was found to be involved as well. A diagnosis o f MF was made. Conclusion: MF should be considered in the differential diagnosis of bilate ral exophthalmos.