Small cell neuroendocrine carcinoma of the cervix with involvement of multiple pelvic nodes - A successfully treated case by multimodal approach

Small cell neuroendocrine carcinoma of the cervix is very rare and is usual ly associated with dismal prognosis if treated by conventional surgery and radiotherapy even in early stage disease. This tumor is characterized by ea rly lymphatic and hematogenous spread. Only one successfully treated case o f small cell neuroendocrine carcinoma of the cervix with dissemination to t he pelvic nodes had been reported before in the literature. We are reportin g a case of small cell neuroendocrine carcinoma of the cervix with multiple pelvic nodal metastases including the common iliac nodes; which had been s uccessfully treated with a multimodal approach including radical hysterecto my, pelvic/para-aortic lymphadenectomy, and. postoperative chemotherapy usi ng cisplatin-etoposide combinations and pelvic irradiation. (C) 1999 Academ ic Press.