Synthesis of bicyclic derivatives of 5A-carba-sugars: 6-hydroxyl group conformationally restricted 5A-carba-D-mannopyranose derivatives

Some bicyclic derivatives of 5a-carba-alpha- and beta-D-mannopyranoses, who se 6-hydroxyl groups are conformationally restricted, have been synthesized in order to provide key components of the trisaccharide mimics designed as inhibitors or substrate analogues useful for elucidation of mechanism and action of GlcNAcT-V.