A new stereoselective synthetic strategy for beta-hydroxy-alpha-amino acids of vancomycin

Citation
Mk. Gurjar et al., A new stereoselective synthetic strategy for beta-hydroxy-alpha-amino acids of vancomycin, HETEROCYCLE, 50(1), 1999, pp. 109-116
Citations number
34
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
50
Issue
1
Year of publication
1999
Pages
109 - 116
Database
ISI
SICI code
0385-5414(19990101)50:1<109:ANSSSF>2.0.ZU;2-H
Abstract
The synthesis of syn and anti beta-hydroxy-alpha-amino acids representing r ings C and E of vancomycin has been achieved starting from (R)- and (S)-Gar ner's aldehydes by a stereocontrolled Grignard arylation reaction.