Substituent effects on the rate of acid-catalysed epimerization of indolo[2,3-a]quinolizidines

Authors
Lounasmaa, M Berner, M Tolvanen, A
Citation
M. Lounasmaa et al., Substituent effects on the rate of acid-catalysed epimerization of indolo[2,3-a]quinolizidines, HETEROCYCLE, 50(1), 1999, pp. 243-250
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
50
Issue
1
Year of publication
1999
Pages
243 - 250
Database
ISI
SICI code
0385-5414(19990101)50:1<243:SEOTRO>2.0.ZU;2-V
Abstract
10-Substituted indolo[2,3-a]quinolizidine derivatives were prepared to stud y the effect of substituents on the epimerization rate. Under the condition s employed, electron withdrawing substituents hindered epimerization and el ectron donating substituents accelerated it.