Studies on isocyanides and related compounds. A facile synthesis of 1-substituted 3-cyano-2-methoxy-3-phenylpyrroles

Authors
Bossio, R Marcaccini, S Pepino, R Torroba, T
Citation
R. Bossio et al., Studies on isocyanides and related compounds. A facile synthesis of 1-substituted 3-cyano-2-methoxy-3-phenylpyrroles, HETEROCYCLE, 50(1), 1999, pp. 463-467
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
50
Issue
1
Year of publication
1999
Pages
463 - 467
Database
ISI
SICI code
0385-5414(19990101)50:1<463:SOIARC>2.0.ZU;2-I
Abstract
A simple one-pot synthesis of 1-substituted 3-cyano-1,2-dihydro-2-oxo-4-phe nyl-2H-pyrroles (8) based on the isocyanide chemistry is described. Compoun ds (8) undergo a facile O-methylation with diazomethane to give the corresp onding 1-substituted 3-cyano-2-methoxy-4-phenylpyrroles (1).