Characterization of Moraxella (Branhamella) catarrhalis lbpB, lbpA, and lactoferrin receptor orf3 isogenic mutants

Authors
Bonnah, RA Wong, H Loosmore, SM Schryvers, AB
Citation
Ra. Bonnah et al., Characterization of Moraxella (Branhamella) catarrhalis lbpB, lbpA, and lactoferrin receptor orf3 isogenic mutants, INFEC IMMUN, 67(3), 1999, pp. 1517-1520
Citations number
22
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
3
Year of publication
1999
Pages
1517 - 1520
Database
ISI
SICI code
0019-9567(199903)67:3<1517:COM(CL>2.0.ZU;2-D
Abstract
Pathogenic members of the family Neisseriaceae produce specific receptors t o acquire iron from their host's lactoferrin and transferrin. Recently, put ative Moraxella catarrhalis lactoferrin receptor genes and a third open rea ding frame (lbpB, lbpA, and orf3) were cloned and sequenced. We describe th e preliminary characterization of isogenic mutants deficient in LbpB, LbpA, or Orf3 protein.