Synthesis, structural characterization, and solution behavior of the firstmononuclear, aqueous aluminum citrate complex

The significance of the interaction between aluminum and citrate in biologi cal media is exemplified by the synthesis, isolation, structural characteri zation, and solution behavior of the first mononuclear aluminum citrate com plex. The chemical and structural features of the low molecular weight alum inum citrate species characterized help gain insight into citrate's ability , as a natural ligand, to enhance aluminum's absorption and thus affect its accumulation and biotoxicity at biological sites.