DESIGN AND SYNTHESIS OF NOVEL NONPEPTIDE CCK-B RECEPTOR ANTAGONISTS

Authors
PADIA JK CHILVERS H DAUM P PINNOCK R SUMANCHAUHAN N WEBDALE L TRIVEDI BK
Citation
Jk. Padia et al., DESIGN AND SYNTHESIS OF NOVEL NONPEPTIDE CCK-B RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 7(7), 1997, pp. 805-810
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
7
Year of publication
1997
Pages
805 - 810
Database
ISI
SICI code
0960-894X(1997)7:7<805:DASONN>2.0.ZU;2-1
Abstract
A novel hybrid series of nonpeptide CCK-B receptor antagonists has bee n designed from two known series derived from asperlicin. An efficient synthesis of 2-aminoquinazolinone, an intermediate for the synthesis of a targeted analog, has been developed. (C) 1997 Elsevier Science Lt d.