INHIBITORY EFFECT ON HT-1080 TUMOR-CELL INVASION IN-VITRO USING 9-(2'-HYDROXYETHYL)ADENINE 2'-PHOSPHATES

Authors
KITADE Y HAYASHI M YATOME C CHAJIMA M NAGASE H
Citation
Y. Kitade et al., INHIBITORY EFFECT ON HT-1080 TUMOR-CELL INVASION IN-VITRO USING 9-(2'-HYDROXYETHYL)ADENINE 2'-PHOSPHATES, Bioorganic & medicinal chemistry letters, 7(7), 1997, pp. 833-836
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
7
Year of publication
1997
Pages
833 - 836
Database
ISI
SICI code
0960-894X(1997)7:7<833:IEOHTI>2.0.ZU;2-B
Abstract
Several 9-(2'-hydroxyethyl)purine 2'-phosphates (2a-c and 3) showed a moderate inhibitory effect of tumor cell invasion using Matrigel These 2'-phosphates (2a-c and 3) also inhibited the activity on type IV col lagen degradation by matrix metalloprotease-9. (C) 1997 Elsevier Scien ce Ltd.